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ISSN 0973 - 0958
INSULIN THERAPY
Insulin
Administration and Storage:
If refrigeration facilities are unavailable, then the currently used vial can be stored at room temperature away from heat and direct sunlight. If vials have to be stored for longer periods, a simple method is for the unopened vials to be stored in the earthen pots, which contain drinking water and are found in most homes where a refrigerator is not present.
Initiation
of Insulin:
There are no precise formulae by which the initial dose can be calculated. The usual total dose of insulin is between 0.5 and 1 unit/kg/day although it is usual to start with a starting dose of 0.25 unit/kg/day.
The usual regimen is to start with a small dose of an intermediate acting insulin about 8-12 units S.C. before breakfast or with a mixture of a short acting insulin and Intermediate acting insulin in small doses.
When stabilized most patients require about 60% of total insulin in the morning and 40% in the evening. However insulin-dosing regimen is highly individualized and it has to be tailor made depending upon the patient’s age, weight, sugar levels and presence of any other condition, which may affect the status of blood sugars.
Often overweight patients may need more insulin due to insulin resistance.
Most of the short acting and the intermediate/long acting insulins
available here may be mixed in the same syringe except Lantus.
Insulins are presently available in strengths of U-40, and U-100.
The patient must ensure that the syringes used by him/her are
compatible with the strength of insulin used.
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